Biophotonic therapy eliminates bacteria and viruses from organs before transplantation

Pig lung being irradiated with red light to inactivate viruses. Method developed by scientists in Brazil and Canada can prevent transmission of diseases to organ recipients. Credit: Cristina Kurachi A new technique for the decontamination of organs before transplantation using ultraviolet and red light irradiation has been developed by Brazilian and Canadian researchers and is … Read more

New imaging reveals previously unseen vulnerabilities of HIV: Breakthrough opens new paths to fight against the deadly virus

Imagine that HIV is a sealed tin can: if you opened it, what would you find inside? An international team led by researchers at the University of Montreal Hospital Research Centre (CRCHUM), Tufts University School of Medicine, and the University of Melbourne think they know. For the first time, they have visualized what the “open … Read more

Researchers offer new insights into how maternal immunity impacts neonatal HSV

Herpes simplex virus type 1 (green fluorescence) incubated with non-neutralizing human sera damaged cells. Credit: Sean A. Taylor Findings from a study published in the journal Science Translational Medicine, led by David Leib, Ph.D., professor and chair of microbiology and immunology at Dartmouth’s Geisel School of Medicine, are offering new insights into neonatal herpes, its … Read more

New HIV vaccine could expose latent virus and kill it

Antiretroviral therapy may soon be obsolete, as scientists have successfully used immune cells to kick the dormant form of HIV out of its hiding place and destroy it. The findings may soon lead to an HIV vaccine.New research brings us closer to an HIV vaccine that could eradicate it completely. According to recent estimates, around … Read more

Cellular protein could take on role of restriction factor for hepatitis B virus

Hepatitis B is a viral liver infection that can lead to acute or chronic conditions. Although there is a vaccine that offers protection against the virus, current treatments which prevent the virus from replicating are not curative for infected individuals. Scientists at the Institut Pasteur working in collaboration with the CNRS have demonstrated that a … Read more

Synthetic antibody rapidly prevents Zika infection in mice and non-human primates

A DNA-encoded monoclonal antibody prevents Zika infection in mice and non-human primates, researchers report April 5 in the journal Molecular Therapy. Injections of synthetic DNA encoding the potent anti-Zika monoclonal antibody ZK190 resulted in high production of ZK190 for weeks to months, effectively controlling infection in all animals. The new platform for monoclonal-antibody gene delivery … Read more

Molecules with strong anti-Zika virus potential: The finding might also have application in developing anti-parasite and antibacterial treatments

The Zika virus is widely known for causing microcephaly and other brain defects in the fetuses of pregnant, infected women. Currently, there are no approved antiviral therapies specifically designed to treat Zika, but researchers at the Advanced Science Research Center (ASRC) at The Graduate Center of The City University of New York, Hunter College, and … Read more

Food additive may influence how well flu vaccines work

Michigan State University scientists have linked a common food preservative to an altered immune response that possibly hinders flu vaccines. The study conducted in mice, presented at the 2019 Experimental Biology meeting in Orlando, Fla., April 7 at 9 a.m., offers up a new potential factor in vaccine effectiveness. Tert-butylhydroquinone, or tBHQ, can be found … Read more

Researchers determine atomic structure of fusion protein of a prokaryotic organism

Many viruses, including that perennial winter affliction, the influenza virus, are protected by a lipid membrane on loan from the host cell. The fusion proteins on the surface of the membrane are tasked with merging the lipid membrane of the virus with that of the cell. After this, the virus is able to slip inside … Read more

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