Causes of Addison’s disease: Adrenal gland disruption, autoimmune conditions, and others

Addison’s illness, or adrenal deficiency, happens when the external layer of the adrenal glands are harmed. Many typically, it is brought on by the body immune system assaulting the glands as if they were damaging germs or infections. Nevertheless, it can be triggered in other methods. The adrenal glands, which form part of the endocrine … Read more

How does bereavement impact the immune system?

Shedding a cherished one is, after all, extremely traumatic; it might additionally shorten lifespan. A current paper opinions many years’ price of analysis into bereavement and its results on the immune system.A current paper discusses loss and the immune system. For years, researchers and laypeople alike have famous that when somebody loses a associate, their … Read more

Releasing an immune system brake could help patients with rare but fatal brain infection: Small-scale, clinical study offers early hope for developing a treatment

PML lesions in the brain. MRI of a PML patient showing significant lesions in the brain (white signal). Credit: Image courtesy of Daniel S. Reich, M.D., Ph.D., NINDS The anti-cancer drug pembrolizumab has shown promise in slowing or stopping the progression of progressive multifocal leukoencephalopathy (PML), a typically fatal infection of the brain caused by … Read more

Immune system is potential culprit in causing cavities, damaging fillings

Collagen after incubation with neutrophils for 24 hours: Image at right depicts a loss of collagen fibril network when incubated with neutrophils. Credit: Russel Gitalis A new study by researchers at the University of Toronto’s Faculty of Dentistry provides the first evidence that the body’s own defence system could be a major contributor to tooth … Read more

Single-cell sequencing reveals landscape of immune cell subtypes in lung cancer tumors: Map of myeloid immune cell subpopulations points to new targets for immunotherapy

The recent emergence of immunotherapy has marked a sea change in research and care for many forms of cancer, bringing new hope to patients and families around the world. For those who respond to treatment, the results can be dramatic. Activation of a patient’s immune system against cancer can kill or shrink tumors and, in … Read more

Releasing an immune system brake could help patients with rare but fatal brain infection

MRI of a PML patient showing significant lesions in the brain (white signal). Credit: Irene Cortese, M.D. The anti-cancer drug pembrolizumab has shown promise in slowing or stopping the progression of progressive multifocal leukoencephalopathy (PML), a typically fatal infection of the brain caused by the JC virus (JCV). This finding comes from a small-scale study … Read more

New HIV vaccine could expose latent virus and kill it

Antiretroviral therapy may soon be obsolete, as scientists have successfully used immune cells to kick the dormant form of HIV out of its hiding place and destroy it. The findings may soon lead to an HIV vaccine.New research brings us closer to an HIV vaccine that could eradicate it completely. According to recent estimates, around … Read more

Single-cell sequencing sheds light on landscape of myeloid cells in lung tumors

The recent emergence of immunotherapy has marked a sea change in research and care for many forms of cancer, bringing new hope to patients and families around the world. For those who respond to treatment, the results can be dramatic. Activation of a patient's immune system against cancer can kill or shrink tumors and, in … Read more

Scientists visualize immune cells fighting blood cancer for the first time

When cancer escapes the immune system, our defenses are rendered powerless and are unable to fight against the disease. Chimeric antigen receptor T cells (CAR T cells) represent a promising immunotherapy strategy, developed with the aim of tackling tumors head-on. But the occurrence of relapse in some patients remains a challenge. Scientists at the Institut … Read more

Immune cells key to predicting cancer outcomes, research suggests

Scientists have identified key changes in immune cells within cancerous tumours that could help improve the development of treatments. The study also found a set of genes that are expressed at high levels in breast cancer tumours and linked to more aggressive cancer types. Researchers say the discoveries offer clues to diagnosis and predicting patient … Read more

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