Mother of 3-DNA baby praises new fertility treatment

A pediatric nurse holds a premature baby after feeding him at Medellín’s General hospital on August 20, 2014 in Medellin, Colombia. A Greek mother of the first baby born using DNA from three people has praised the revolutionary technique The Greek mother of the first baby born using DNA from three people on Friday praised … Read more

SRC-1 gene variants linked to human obesity

Credit: CC0 Public Domain Maintaining a healthy body weight is no simple matter. A better understanding of how the body regulates appetite could help tip the scale toward the healthy side. Contributing toward this goal, a team led by researchers at Baylor College of Medicine and the University of Cambridge reports in the journal Nature … Read more

Researchers identify rare SRC-1 gene variants related to human obesity

Maintaining a healthy body weight is no simple matter. A better understanding of how the body regulates appetite could help tip the scale toward the healthy side. Contributing toward this goal, a team led by researchers at Baylor College of Medicine and the University of Cambridge reports in the journal Nature Communications that the gene … Read more

‘Three-person’ baby born in medical ‘revolution’ in Greece

File photo of in-vitro fertilisation, in which eggs were harvested from a woman’s ovaries, fertilised, and then cryogenically preserved. (Photo: AFP) ATHENS: A team of Greek and Spanish doctors announced Thursday (Apr 11) the birth of a baby using DNA from three people after a controversial fertility treatment that has provoked intense ethical debate. The team … Read more

Rare gut condition is more predictable from individual’s genetic makeup, study finds

Hirschsprung disease – a rare condition where the failure of gut nerves to develop before birth leads to impaired bowel contractions that prevent infants from passing stool – is more predictable from an individual's genetic makeup than previously envisioned. This is the finding of a study published online in the April 11 edition of the … Read more

Three-person baby born in medical ‘revolution’

Credit: CC0 Public Domain A team of Greek and Spanish doctors announced Thursday the birth of a baby using DNA from three people after a controversial fertility treatment that has provoked intense ethical debate. The team used an egg from the infertile mother, the father’s sperm and another woman’s egg to conceive the baby boy, … Read more

New strategy for editing and repairing genetic mutation associated with microduplications

Scientists at UMass Medical School have developed a strategy for editing and repairing a particular type of genetic mutation associated with microduplications using CRISPR/Cas9 and a seldom-used DNA repair pathway. Described in Nature, this approach to programmable gene editing overcomes prior inefficiencies in gene correction. "It's like hitting the reset button," said Scot A. Wolfe, … Read more

Can genetic variants predict depression risk in young people?

A new study looks at the genetic makeup of thousands of adults with depression to try to find an accurate way of predicting which children and adolescents may be at risk of developing this mental health problem. Researchers identify a genetic risk score that could help predict depression risk in the young. Many factors determine … Read more

Cancer: Scientists find 129 ‘jumping genes’ that drive tumor growth

In cancer research, scientists usually look for cancer genes by scouring the genome for altered sequences — or mutations — in DNA. But a new study has now revealed that jumping genes, which customary sequencing overlooks, are also important drivers of tumor growth.Researchers have uncovered 129 jumping genes that may drive cancer. Scientists at the … Read more

Genetic defects without consequences

Genetic compensation does not appear in the absence of mutant mRNA. The figure shows the vascular system in a two-day old zebrafish embryo. When the mRNA derived from a defective gene is absent, the vascular system does not develop properly (lower image). Credit: MPI for Heart and Lung Research. Many diseases are caused by genetic … Read more

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