The Quest For the Roots of Autism — and What It Says About Us All

( Credit: Brian Stauffer/brianstauffer. com) As alarm grew over autism occurrence at the turn of this century, there was much public talk of a growing “epidemic.” That language has actually because softened, and it is now clear that numerous autistic individuals existed all along, their condition unacknowledged till fairly just recently. However what is the … Read more

Catalent seeks slice of gene therapy market with Paragon buy

REUTERS: Agreement drugmaker Catalent Inc stated on Monday it would purchase independently held Apotheosis Bioservices Inc for US$ 1.2 billion in money, reinforcing its abilities to make gene treatment drugs for its biotech customers. Apotheosis, backed by private-equity companies Camden Partners and NewSpring Capital, concentrates on establishing and making intricate biopharmaceuticals for its customers and … Read more

SRC-1 gene variants linked to human obesity

Credit: CC0 Public Domain Maintaining a healthy body weight is no simple matter. A better understanding of how the body regulates appetite could help tip the scale toward the healthy side. Contributing toward this goal, a team led by researchers at Baylor College of Medicine and the University of Cambridge reports in the journal Nature … Read more

Researchers identify rare SRC-1 gene variants related to human obesity

Maintaining a healthy body weight is no simple matter. A better understanding of how the body regulates appetite could help tip the scale toward the healthy side. Contributing toward this goal, a team led by researchers at Baylor College of Medicine and the University of Cambridge reports in the journal Nature Communications that the gene … Read more

Scientists develop new approach to unravel toxic effects of multiple stressors

Genomic markers are the key in a new approach for assessing the toxic effects arising from exposure to multiple stressors. As the number of new chemicals used in industry, food and consumer products is constantly increasing, so is the chemical release to the environment, and the need to understand the adverse effects of chemical mixtures … Read more

Bacteria share genes with one another, even across tissue boundaries

Bacteria in the human body are sharing genes with one another at a higher rate than is typically seen in nature, and some of those genes appear to be traveling – independent of their microbial hosts – from one part of the body to another, researchers report in the journal Scientific Reports. The findings are … Read more

New strategy for editing and repairing genetic mutation associated with microduplications

Scientists at UMass Medical School have developed a strategy for editing and repairing a particular type of genetic mutation associated with microduplications using CRISPR/Cas9 and a seldom-used DNA repair pathway. Described in Nature, this approach to programmable gene editing overcomes prior inefficiencies in gene correction. "It's like hitting the reset button," said Scot A. Wolfe, … Read more

Chinese researchers add human brain-related gene to monkey genome in controversial experiment

Credit: CC0 Public Domain A team of researchers working in China has created several transgenic rhesus monkeys by adding a human gene involved in brain growth to the monkey’s genome. In their paper published in the National Science Review, the group describes their work and the testing they conducted on the monkeys after they were … Read more

Mapping cellular diversity by looking for common topics of gene control

A Belgian team of computational biologists led by Stein Aerts (VIB-KU Leuven) has developed a new bioinformatics method called cisTopic. Inspired by text-mining methods, cisTopic helps scientists to gain insight into the mechanisms underlying the differences in gene regulation across and within the cells in our body by looking for common topics. In a new … Read more

Genetic defects without consequences

Genetic compensation does not appear in the absence of mutant mRNA. The figure shows the vascular system in a two-day old zebrafish embryo. When the mRNA derived from a defective gene is absent, the vascular system does not develop properly (lower image). Credit: MPI for Heart and Lung Research. Many diseases are caused by genetic … Read more

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