Study reports repair of mitochondrial recycling defect linked to Parkinson’s disease

Treating mice which have a Parkinson’s disease-causing mutation with a small molecule compound restores the removing of broken mitochondria from their mind cells, exhibits a examine printed right now in eLife. The findings might assist clarify what goes improper in dopamine-producing mind cells in individuals with mutations that trigger Parkinson’s illness. Parkinson’s illness is attributable … Read more

Near-atomic look at three ways to thwart SARS-CoV-2 variants

SARS-CoV-2 nanobodies — microscopic molecules developed on the College of Pittsburgh College of Drugs that neutralize the virus in animals — are remarkably lively in opposition to mutations present in variants, together with Delta, in line with new analysis by Pitt and Case Western Reserve College scientists. The findings, introduced in the present day in … Read more

A new way to treat PTSD?

Credit score: CC0 Public Area Publicity to a traumatic expertise can result in post-traumatic stress dysfunction (PTSD), an incapacitating dysfunction in prone individuals with no dependable remedy. Significantly puzzling is knowing how transient publicity to trauma creates persistent long- time period affected by PTSD and why some persons are prone to PTSD whereas others that … Read more

Study identifies DNA signatures linked to heart disease

A double stranded DNA fragment. Credit score: Vcpmartin/Wikimedia/ CC BY-SA 4.0 A brand new examine identifies DNA signatures related to danger for heart problems, a discovery that would result in alternatives for scientific intervention years earlier than signs manifest. Primarily based on analyses of knowledge from 5 massive coronary heart cohort research of numerous populations, … Read more

Certain dermoscopic structures linked to melanoma detection

(HealthDay)—Sure dermoscopic constructions related to melanoma detection could have diagnostic significance, together with shiny white constructions, pseudopods, and blue-white veil, in response to a scientific overview and meta-analysis revealed on-line Aug. Four in JAMA Dermatology. Natalie M. Williams, M.D., from the College of Miami Miller College of Drugs, and colleagues examined the diagnostic accuracy of … Read more

Understanding the inflammation that causes death in COVID-19 patients

FIG 1 The large elevation of plasma Gal-9 discriminates COVID-19 sufferers from wholesome topics. (A) Detected concentrations of Gal-9 within the plasma specimens of COVID-19-infected people in comparison with wholesome controls (HCs) as measured by ELISA. (B) Detected plasma ranges of Gal-9 in COVID-19 sufferers with gentle/average or extreme illness versus HCs. (C and D) Evaluating … Read more

COVID vaccines an opportunity for Big Pharma to reset its reputation after decades of big profits and scandals

The worth of Epipens rose by greater than 400%. Credit score: Shutterstock Simply weeks earlier than the primary COVID-19 circumstances emerged, Gallup revealed its newest ballot on America’s views about enterprise. On the backside of the checklist of 25 sectors was the pharmaceutical {industry}. Beneath promoting. Beneath oil and fuel. Beneath the banks. The pandemic … Read more

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