‘Where does it hurt?’ predicts chronic pain outcomes, study shows

Heatmap with physique map area on horizontal axis and every row on the vertical axis representing a person affected person out of your complete cohort (N = 21,658 distinctive sufferers) organized by cluster membership. Credit score: Alter et al, 2021, PLOS ONE (CC-BY 4.0, creativecommons.org/licenses/by/4.0/) Ache distribution as reported on a physique map, by itself, … Read more

Nutritional value of foods static despite targets on calories, salt and sugar

Complete sales-weighted nutrient profiling rating by firm and yr. Credit score: Bandy et al, 2021, PLOS ONE (CC-BY 4.0, creativecommons.org/licenses/by/4.0/) UK insurance policies that set targets for reductions in salt, sugar and energy haven’t led to general enhancements within the dietary worth of meals merchandise. Analysis revealed within the open entry journal PLOS ONE evaluates … Read more

Applying lessons learned from the tobacco settlement to opioid negotiations

Studying the exhausting means The 1998 $206 billion settlement with the tobacco business could supply classes as authorities officers negotiate with the drug corporations that manufacture opioids. iStock Allan Brandt, historical past of science scholar and ‘Cigarette Century’ writer, says opioid negotiators ought to heed classes from tobacco settlement As state and native officers weigh … Read more

Study tracks global death toll of COVID-19 pandemic

New perception on the dying toll of the COVID-19 pandemic worldwide has been printed within the open-access eLife journal. Evaluating the affect of COVID-19 between international locations or throughout a given time period is difficult as a result of reported numbers of circumstances and deaths might be affected by testing capability and reporting coverage. The … Read more

Study reports repair of mitochondrial recycling defect linked to Parkinson’s disease

Treating mice which have a Parkinson’s disease-causing mutation with a small molecule compound restores the removing of broken mitochondria from their mind cells, exhibits a examine printed right now in eLife. The findings might assist clarify what goes improper in dopamine-producing mind cells in individuals with mutations that trigger Parkinson’s illness. Parkinson’s illness is attributable … Read more

Near-atomic look at three ways to thwart SARS-CoV-2 variants

SARS-CoV-2 nanobodies — microscopic molecules developed on the College of Pittsburgh College of Drugs that neutralize the virus in animals — are remarkably lively in opposition to mutations present in variants, together with Delta, in line with new analysis by Pitt and Case Western Reserve College scientists. The findings, introduced in the present day in … Read more

A new way to treat PTSD?

Credit score: CC0 Public Area Publicity to a traumatic expertise can result in post-traumatic stress dysfunction (PTSD), an incapacitating dysfunction in prone individuals with no dependable remedy. Significantly puzzling is knowing how transient publicity to trauma creates persistent long- time period affected by PTSD and why some persons are prone to PTSD whereas others that … Read more

Study identifies DNA signatures linked to heart disease

A double stranded DNA fragment. Credit score: Vcpmartin/Wikimedia/ CC BY-SA 4.0 A brand new examine identifies DNA signatures related to danger for heart problems, a discovery that would result in alternatives for scientific intervention years earlier than signs manifest. Primarily based on analyses of knowledge from 5 massive coronary heart cohort research of numerous populations, … Read more

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